Contract Research
Hooke offers contract research for evaluation of drug efficacy in rodents. Our staff has extensive experience developing new models and testing drug candidates in commonly used models of autoimmune diseases and cancer.
We are continuously introducing additional models in other areas of basic research.
Our Services
Hooke can perform all elements of your study, including:
- Disease induction
- Efficacy testing
- Clinical observation
- Blood & histological analysis
- FACS analysis of cellular infiltrates
- Statistical analysis
- Report preparation
- Interpretation of results
Why Hooke?
- Quality & Price
Our 100% focus on rodent in vivo research lets us work efficiently, and our low-cost rodent facility in Lawrence, Massachusetts (30 minutes north of Cambridge) keeps our prices very competitive, while delivering first-class science.
- Flexibility
We can do as much or as little work as you need – with no up-front investment or setup effort from you.
- Expertise
Each model we offer has been established in our lab by an experienced scientist with multiple published papers in that research area. In addition to running your study, we can provide valuable expertise and interpretation of results.
By specializing in rodent in vivo work, we can do the job more efficiently and at less total cost to you. We are committed to providing first class science at very competitive prices.
Models Offered
- Asthma
- OVA-induced asthma in BALB/C mice
- OVA-induced asthma in C57BL/6 mice
- Collagen-induced arthritis (CIA)
- CIA in DBA/1 mice
- Experimental autoimmune encephalomyelitis (EAE)
- MOG35-55/CFA-induced EAE in C57BL/6 mice
- PLP139-151/CFA-induced, remitting-relapsing EAE in SJL mice
- Adoptive transfer EAE in SJL mice
- Adoptive transfer EAE in C57BL/6 mice
- Inflammatory bowel disease (IBD)
- DSS-induced colitis
- TNBS-induced colitis
- Oxazolone-induced colitis
- CD4+CD45RBhigh cell transfer into SCID mice
- LPS-induced shock
Available on Request
- Air pouch model for cell trafficking
- Passive cutaneous anaphylaxis
- Passive systemic anaphylaxis
- Development of new or optimized models
We are continuously introducing additional models in our laboratory; please contact us for information about models not listed.
Please contact us for a detailed quotation.
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